Mysterious deaths and disappearances ramp up in the city. Meanwhile, a doctor makes a frightening discovery, and a local reporter becomes tomorrow’s headline.

From Nazis and serial killers to mutants and aliens, no one is safe inside the walls of the Briarcliff Mental Institution. In a house of healing that is anything but, troubled nun Sister Jude rules with an iron fist and Dr Arden conducts strange experiments on the facility's patients.