In 1952, in the quiet, sleepy hamlet of Jupiter, Florida, a troupe of human "curiosities" has just arrived in town, coinciding with the strange emergence of a dark entity that savagely threatens the lives of townsfolk and freaks alike.

The few remaining Salem descendants are under assault by forces of ignorance and hate. The young witches seek refuge at Miss Robichaux's Academy in New Orleans, including new arrival, Zoe, who harbors a terrifying secret of her own. Fiona, a Supreme Witch with unimaginable powers, is determined to protect the Coven, but her obsessive quest for immortality will lead her to cross paths with a voodoo queen and a murderous slave owner cursed with eternal life.